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Aug
30 |
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comment |
finding and replacing a string within a line with an if statement I sometimes want to replace only the second instance. For example, this is a usual few lines of the text file 'Cg200 <abxcd> {10} ; 34 USC_1320-496-0 <hkxhk> {01} ; 51' In line 1, the change should be ab to ba only because of the {01},while in line 2 the change should be hk to kh for the second instance only. |
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Aug
30 |
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asked | finding and replacing a string within a line with an if statement |
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Apr
17 |
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comment |
Testing for a significant difference between ML estimates: Likelihood ratio or Wald test? Any ideas on how to code the LRT in R? |
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Apr
17 |
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Testing for a significant difference between ML estimates: Likelihood ratio or Wald test? @Ernest : I have not gotten that before...I think my llhood equations must be set up wrong when I incorporate both data sets and estimate 4 parameters.... |
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Apr
17 |
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awarded | Supporter |
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Apr
17 |
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awarded | Editor |
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Apr
17 |
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revised |
Testing for a significant difference between ML estimates: Likelihood ratio or Wald test? added 1666 characters in body |
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Apr
17 |
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comment |
Testing for a significant difference between ML estimates: Likelihood ratio or Wald test? @Ernest ok. In the setup you just described, is L1 the reduced or constrained model (where s1=s2?) -- I tried to setup a new likelihood where s is the same for both sets of data and i sum the likelihoods Lnull(s1=s2,d,data1, data2) and then he unrestricted L2(s1,s2,d,data1 data2) where I estimate each s seperately and sum the resultant likelihoods. But the unrestricted likelihood, L2, returns "needs finite values of fn". |
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Apr
17 |
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comment |
Testing for a significant difference between ML estimates: Likelihood ratio or Wald test? @guest OK. Any suggestion how to code that to a single call to optim()? I have two different sets of genotype data (one for each environment) that Id have to work in. I also have two unknowns, s and d. so I have to do this for s1=s2 and d1=d2. |
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Apr
16 |
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asked | Testing for a significant difference between ML estimates: Likelihood ratio or Wald test? |
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Apr
16 |
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comment |
further hypothesis testing for the difference in ML estimates after optim in R @ernest Ok. I dont really know the sampling distribution of s. It is being estimated from genotype data under a simple fitness model seperately in two environments. I was hoping that I could use the estimated variance from the hessian and the point estimate to do some simple post-hoc hypothesis testing of whether the estimate of s in one environment is statistically different from the s in the other environment (does selection change across environments). Is a wald test appropriate? If I could simply estimate a difference parameter, I could test it against zero... |
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Apr
16 |
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awarded | Student |
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Apr
16 |
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awarded | Student |
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Apr
15 |
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awarded | Editor |
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Apr
15 |
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asked | further hypothesis testing for the difference in ML estimates after optim in R |
